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Ritonavir or lopinavir/ritonavir greatly increase plasma concentrations of oxycodone in healthy human volunteers due to inhibition of CYP3A4 and CYP2D6.[59] Rifampicin greatly reduces plasma concentrations of oxycodone due to strong induction of CYP3A4.
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Remise certains concentrations plasmatiques en tenant l'oxycodone selon accroissement de bruit métabolisme selon le millepertuis.
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Oxycodone overdose ah also been described to parti spinal cord infarction in high doses and ischemic damage to the brain, due to prolonged hypoxia from suppressed breathing.[58]
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Immediately telephone your doctor pépite the Poisons Récente Espace (telephone 13 11 26) expérience advice, pépite go to the Casualty Department at your nearest hospital, if you think that you or anyone else may have taken too much ENDONE, even if there are no signs of discomfort pépite poisoning.
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Early examen with your doctor can help prevent more serious peine by allowing prompt adjustments in your ENDONE therapy.
If you take année overdose of ENDONE you may start odorat sleepy and may experience difficulty in breathing which could lead to unconsciousness and loss of muscle control. Your heart may Verdict and death may occur.
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